SUPRAMOLECULAR AGGREGATES PORPHYRINS-PHTHALOCYANINES AND THEIR IMPLICATIONS IN PHOTOMEDICINE
Simona-Florentina Pop, Rodica-Mariana Ion
Pagini: 350-358
Publicat: 1 Jan 2009
Vizualizări: 169
Descărcări: 17
Rezumat: The aggregates of porphyrins and phtalocyanines can provide promising properties in the search of new molecular materials for medicine, and could be readily monitored spectroscopically, since it causes strong perturbations of their absorption spectra. The formation of water-soluble heteroaggregates from Ni,Co,Pd,Rh complexes of 5,10,15,20-tetra-methyl-pyrydil porphyrin (MeTMPyP) and Zn complex of 2,9,16,23-tetra-carboxylate-phthalocyanine (ZnTCPc) has been investigated in this paper by using UV-Vis and IR spectra. The formation of such adducts involves intensive interactions between two differently charged macrocycles. The singlet oxygen generation is also stimulated by this heteroaggregation. Some data about the application of such heteroaggregates in photodynamic therapy of Saccharomices Cerevisiae cells were evaluated.
Cuvinte cheie: porphyrins, phthalocyanine, heteroaggregates, photodynamic therapy
Citează acest articol: Simona-Florentina Pop, Rodica-Mariana Ion. SUPRAMOLECULAR AGGREGATES PORPHYRINS-PHTHALOCYANINES AND THEIR IMPLICATIONS IN PHOTOMEDICINE. Journal of International Scientific Publications: Materials, Methods & Technologies 3, 350-358 (2009). https://www.scientific-publications.net/en/article/1003492/
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