SUBACUTE TOXICOLOGICAL EFFECTS OF EMAMECTINE BENZOATE ON WISTAR RAT TESTES: HISTOPATHOLOGICAL CHANGES, DETERMINATION OF EMAMECTIN BENZOATE RESIDUES BY UPLC-MS/MS AND PROTECTIVE EFFECT OF VITAMIN C
Hassina Khaldoun-Oularbi, Delphine Allorge, Nacira Zerrouki-Daoudi, Camille Richeval, Hadjer Aissani, Nadia Djennas, Mounia Baha
Pages: 365-374
Published: 23 May 2015
Views: 3,094
Downloads: 996
Abstract: Emamectin benzoate (Proclaim®) is a biopesticide derivative of the avermectins developed for the control of insect pests. In the present study, the ameliorating effect of vitamin C was examined histologically and biochemically in testicle tissue of male Wistar rats, Rattus norvegicus, exposed to emamectin benzoate (EMB). Male rats (n=21) were allocated into 3 groups of seven each: Group I served as control rats; Group II was given daily EMB at dose of 10 mg/kg b.w. by gavage. Group III received EMB (10 mg/kg b.w.) and were co administered with vitamin C intraperitoneally (200 mg/kg/day) during 28 days. Rats were followed-up for an additional 14 day-period to detect delayed occurrence or persistence of toxic effects.
Keywords: emamectin benzoate, testes, vitamin c, histopathology, uplc-ms/ms, rat
Cite this article: Hassina Khaldoun-Oularbi, Delphine Allorge, Nacira Zerrouki-Daoudi, Camille Richeval, Hadjer Aissani, Nadia Djennas, Mounia Baha. SUBACUTE TOXICOLOGICAL EFFECTS OF EMAMECTINE BENZOATE ON WISTAR RAT TESTES: HISTOPATHOLOGICAL CHANGES, DETERMINATION OF EMAMECTIN BENZOATE RESIDUES BY UPLC-MS/MS AND PROTECTIVE EFFECT OF VITAMIN C. Journal of International Scientific Publications: Agriculture & Food 3, 365-374 (2015). https://www.scientific-publications.net/en/article/1000691/
Download full text
Back to the contents of the volume
© 2024 The Author(s). This is an open access article distributed under the terms of the
Creative Commons Attribution License https://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This permission does not cover any third party copyrighted material which may appear in the work requested.
Disclaimer: The opinions and claims presented in this article are solely those of the authors and do not necessarily reflect the views of their affiliated organizations, the publisher, editors, or reviewers.
