SYNTHESIS AND STRUCTURE OF NEW BENZOTHIAZOLE HYBRIDS AS POTENTIAL ANTICANCER AGENTS
Yordan Stremski, Stela Statkova-Abeghe, Desislava Kirkova, Plamen Angelov, Iliyan Ivanov
Pages: 173-187
Published: 23 Sep 2021
Views: 603
Downloads: 58
Abstract: (Benzo)thiazole hybrids are target molecules in synthetic chemistry studied nowadays according their important bioactive potential. In this mini-review we illustrate an effective one-pot method for the synthesis of various groups 2-substituted benzothiazoles as potential anticancer agents. The reaction conditions for an α-amidoalkylation /oxidation sequence toward thiazole-containing heterocycles are studied and optimized.
Keywords: (benzo)thiazole hybrids, α-amidoalkylation, one-pot reactions, anticancer drug candidates
Cite this article: Yordan Stremski, Stela Statkova-Abeghe, Desislava Kirkova, Plamen Angelov, Iliyan Ivanov. SYNTHESIS AND STRUCTURE OF NEW BENZOTHIAZOLE HYBRIDS AS POTENTIAL ANTICANCER AGENTS. Journal of International Scientific Publications: Materials, Methods & Technologies 15, 173-187 (2021). https://www.scientific-publications.net/en/article/1002209/
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