GREEN SYNTHESIS OF NEW HYBRID MOLECULES OF IBUPROFEN AND 1,2,3,4-TETRAHYDROISOQUINOLINE
Radostina R. Miladinova, Stanimir P. Manolov, Iliyan I. Ivanov, Dimitar G. Bojilov
Pages: 195-201
Published: 23 Sep 2021
Views: 422
Downloads: 46
Abstract: Herein we report an eco-friendly method for synthesis of 1,2,3,4-tetrahydroisoquinoline derivatives of ibuprofen. All five newly obtained compounds are fully characterized with their 1H,13C-NMR, IR, HRMS, and are interesting for the purpose of studying their biological activities.
Keywords: ibuprofen, nsaids, hybrids, 1,2,3,4-tetrahydroisoquinoline, green chemistry, tfoh/sio2
Cite this article: Radostina R. Miladinova, Stanimir P. Manolov, Iliyan I. Ivanov, Dimitar G. Bojilov. GREEN SYNTHESIS OF NEW HYBRID MOLECULES OF IBUPROFEN AND 1,2,3,4-TETRAHYDROISOQUINOLINE. Journal of International Scientific Publications: Materials, Methods & Technologies 15, 195-201 (2021). https://www.scientific-publications.net/en/article/1002211/
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