SYNTHESIS OF 1-BIPHENYL-4-ARYL-1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES AS STRUCTURAL ANALOGUES OF THE ALKALOID CHERYLLINE
Stanimir P. Manolov, Stoyanka N. Atanasova, Iliyan I. Ivanov
Pages: 424-431
Published: 1 Jan 2013
Views: 60
Abstract: The biological activity of isoquinoline derivatives, as analogues of various drugs, has provided great deal of interest for the synthesis of new compounds.An application of Bischler-Napieralski reaction for the synthesis of new 1,2,3,4-tetrahydroisoquinolines with biphenyl substituent on the 1st position and aryl substituent on 4th position, is described.
Keywords: cherylline, 4-aryl-tetrahydroisoquinoline, 1-biphenyl-tetrahydroisoquinolines, bischlernapieralski reaction
Cite this article: Stanimir P. Manolov, Stoyanka N. Atanasova, Iliyan I. Ivanov. SYNTHESIS OF 1-BIPHENYL-4-ARYL-1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES AS STRUCTURAL ANALOGUES OF THE ALKALOID CHERYLLINE. Journal of International Scientific Publications: Materials, Methods & Technologies 7, 424-431 (2013). https://www.scientific-publications.net/en/article/1003072/
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