SYNTHESIS AND SPECTRAL CHARACTERIZATION OF NEW SALVADORICINE ANALOGUES
Yordan Stremski, Stela Statkova-Abeghe, Iliyan Ivanov, Mladen Naydenov
Pages: 137-143
Publié: 6 Sep 2018
Vues: 2,482
Téléchargements: 323
Citations: 3 (Google Scholar)
Résumé: Salvadoricine is an indole alkaloid isolated from the leaves of Salvadora persica Linn. This natural product has interesting and diverse biological profile. An effective one-pot synthesis of Salvadoricine analogues via multicomponent reaction of α-amidoalkylation is proposed. The conditions for the reaction of benzothiazole, alkyl chloroformates and 3-acetylindole were found. The structure of the obtained in good yields analogues of natural alkaloid - Salvadoricine was proved by spectral methods.
Mots-clés : salvadoricine, benzothiazole derivatives, α-amidoalkylation, multicomponent reactions
Citer cet article : Yordan Stremski, Stela Statkova-Abeghe, Iliyan Ivanov, Mladen Naydenov. SYNTHESIS AND SPECTRAL CHARACTERIZATION OF NEW SALVADORICINE ANALOGUES. Journal of International Scientific Publications: Materials, Methods & Technologies 12, 137-143 (2018). https://www.scientific-publications.net/en/article/1001689/
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