SYNTHETIC ANALOGUES OF ALKALOID CHERYLLINE
Stanimir Manolov, Iliyan Ivanov, Stoyanka Nikolova
Pagini: 134-140
Publicat: 1 Jan 2011
Vizualizări: 349
Descărcări: 41
Rezumat: An application of a-amidoalkylation reaction, as an alternative efficient synthesis of analogues of cherylline, is reported. The required for this purpose amides would arise from reaction of aminoacetaldehyd-dimethylacetal with veratrole (1,2-dimetoxybenzene) in polyphosphoric acid, followed by acylation of obtained amines with different acid chlorides or sulfochlorides. Variety of reaction conditions – acidity of milieu, temperature and reaction time, were used for optimization the conditions for the final cyclization stage
Cuvinte cheie: cherylline, 4-aryl- tetrahydroisoquinolines, a-amidoalkylation reaction
Citează acest articol: Stanimir Manolov, Iliyan Ivanov, Stoyanka Nikolova. SYNTHETIC ANALOGUES OF ALKALOID CHERYLLINE. Journal of International Scientific Publications: Materials, Methods & Technologies 5, 134-140 (2011). https://www.scientific-publications.net/en/article/1003327/
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