SYNTHETIC ANALOGUES OF ALKALOID CHERYLLINE
Stanimir Manolov, Iliyan Ivanov, Stoyanka Nikolova
Pages: 134-140
Published: 1 Jan 2011
Views: 89
Abstract: An application of a-amidoalkylation reaction, as an alternative efficient synthesis of analogues of cherylline, is reported. The required for this purpose amides would arise from reaction of aminoacetaldehyd-dimethylacetal with veratrole (1,2-dimetoxybenzene) in polyphosphoric acid, followed by acylation of obtained amines with different acid chlorides or sulfochlorides. Variety of reaction conditions – acidity of milieu, temperature and reaction time, were used for optimization the conditions for the final cyclization stage
Keywords: cherylline, 4-aryl- tetrahydroisoquinolines, a-amidoalkylation reaction
Cite this article: Stanimir Manolov, Iliyan Ivanov, Stoyanka Nikolova. SYNTHETIC ANALOGUES OF ALKALOID CHERYLLINE. Journal of International Scientific Publications: Materials, Methods & Technologies 5, 134-140 (2011). https://www.scientific-publications.net/en/article/1003327/
Back to the contents of the volume
© 2026 The Author(s). This is an open access article distributed under the terms of the
Creative Commons Attribution License https://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This permission does not cover any third party copyrighted material which may appear in the work requested.
Disclaimer: The Publisher and/or the editor(s) are not responsible for the statements, opinions, and data contained in any published works. These are solely the views of the individual author(s) and contributor(s). The Publisher and/or the editor(s) disclaim any liability for injury to individuals or property arising from the ideas, methods, instructions, or products mentioned in the content.
