IN VITRO AND IN SILICO BIOLOGICAL ACTIVITY OF NEW IBUPROFEN HYBRIDS
Stanimir P. Manolov, Iliyan I. Ivanov, Dimitar G. Bojilov
Страницы: 202-211
Опубликовано: 23 Sep 2021
Просмотры: 1,852
Загрузки: 206
Аннотация: Herein we report the biological evaluation of new hybrids of 1,2,3,4-tetrahydroisoquinoline with ibuprofen. The hybrids are screened for their in vitro inhibition of albumin denaturation, antioxidant, and antitryptic activity. The tested compounds have shown significant results. The lipophilicity was established using both reversed-phase thin layer chromatography and in silico calculations.
Ключевые слова: in vitro, in silico, ibuprofen, nsaids, anti-inflammatory, antitryptic, antioxidant activity
Цитировать эту статью: Stanimir P. Manolov, Iliyan I. Ivanov, Dimitar G. Bojilov. IN VITRO AND IN SILICO BIOLOGICAL ACTIVITY OF NEW IBUPROFEN HYBRIDS. Journal of International Scientific Publications: Materials, Methods & Technologies 15, 202-211 (2021). https://www.scientific-publications.net/en/article/1002212/
Вернуться к содержанию тома
© 2026 The Author(s). This is an open access article distributed under the terms of the
Creative Commons Attribution License https://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This permission does not cover any third party copyrighted material which may appear in the work requested.
Disclaimer: The Publisher and/or the editor(s) are not responsible for the statements, opinions, and data contained in any published works. These are solely the views of the individual author(s) and contributor(s). The Publisher and/or the editor(s) disclaim any liability for injury to individuals or property arising from the ideas, methods, instructions, or products mentioned in the content.
