EFFECT OF THE MAIN NON-BIOLOGICAL DISEASE MODIFYING ANTIRHEUMATIC DRUGS ON RADIOGRAPHIC PROGRESSION IN PATIENTS WITH DIFFERENT DURATION OF RHEUMATOID ARTHRITIS
Oleg Iaremenko, Ganna Mykytenko, Dmitro Fedkov
Страници: 421-431
Публикувана: 1 Jan 2013
Преглеждания: 629
Изтегляния: 60
Резюме: In this clinical study, the effect of methotrexate (MTX), leflunomide (LF), sulfasalazine (SS) and the combination of disease modifying antirheumatic drugs (DMARDs) on radiological progression in patients with very early, early and advanced rheumatoid arthritis (RA) was determined. It was found that the effectiveness of all variants of DMARD therapy in very early and early RA is equal, while in advanced RA, LF and CBT are significantly superior to MTX and SS. The most important determinants of radiological progression of very early RA are level of antibodies to cyclic citrullinated peptide (anti-CCP) and total radiographic score, early RA - the presence of anti-CCP and total radiographic score, advanced RA - erosion score, level of anti-CCP, elevated levels of CRP and ESR value.
Ключови думи: rheumatoid arthritis, disease duration, disease modifying antirheumatic drugs, radiological progression
Цитирайте тази статия: Oleg Iaremenko, Ganna Mykytenko, Dmitro Fedkov. EFFECT OF THE MAIN NON-BIOLOGICAL DISEASE MODIFYING ANTIRHEUMATIC DRUGS ON RADIOGRAPHIC PROGRESSION IN PATIENTS WITH DIFFERENT DURATION OF RHEUMATOID ARTHRITIS. Journal of International Scientific Publications: Materials, Methods & Technologies 7, 421-431 (2013). https://www.scientific-publications.net/en/article/1003124/
Обратно към съдържанието на тома
© 2026 The Author(s). This is an open access article distributed under the terms of the
Creative Commons Attribution License https://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This permission does not cover any third party copyrighted material which may appear in the work requested.
Disclaimer: The Publisher and/or the editor(s) are not responsible for the statements, opinions, and data contained in any published works. These are solely the views of the individual author(s) and contributor(s). The Publisher and/or the editor(s) disclaim any liability for injury to individuals or property arising from the ideas, methods, instructions, or products mentioned in the content.
