MODELING OF BATCH CULTIVATION OF SACCHAROMYCES CEREVISIAE USING DIFFERENT MIXING SYSTEMS
Published: 2 Jun 2014
Abstract: Mathematical models in different mixing conditions (impulse and vibromixing) in a Saccharomyces cerevisiae batch cultivation are presented in this work. Six models were investigated for the following specific grown rate: Monod, Aiba, Andrews, Haldane, Luong, and Edward. For the parameter identification, we considered the worst observed error for all experiments as an objective function. This approach is a special case of multi objective parameter estimation problems so that the parameter estimation problem becomes a min–max problem. The obtained results (correlation quotients, Fisher function, relative error and statisticsλ) show all models for the specific grown rates are adequate and they can be used for modelling of the specific grown rate for the different mixing systems. However, the best statistical indicators Luong have for the model for impulse mixing and Haldane model for the vibromixing, and they will be used in a model the process of mixing the two systems.
Keywords: specific grown rate, different mixing systems, min–max problem, modelling
Download full text
Back to the contents of the volume
© 2019 The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/
, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This permission does not cover any third party copyrighted material which may appear in the work requested.