EVALUATION OF THE BIOACTIVITY PROPERTIES OF SILVER DOPED HYDROXYAPATITE DEPENDING ON THE PREPARATION METHOD
L. Poca, A. Dubnika, D. Loca, L. Berzina-Cimdina
Pages: 612-620 Published: 2 Jun 2014
Views: 2,066 Downloads: 1,692
Abstract: In the present study in vitro bioactivity properties of silver doped hydroxyapatite (HAp/Ag) ceramic scaffolds were evaluated. HAp/Ag powder samples with 0.3 - 2.0 wt % of silver were prepared by two different modified wet precipitation methods at 90°C temperature. The Obtained fine HAp/Ag powder was used to prepare dense and porous HAp/Ag ceramic scaffolds. The bioactivity properties of dense and porous HAp/Ag ceramics scaffolds were determined in simulated body fluid (SBF). The scanning electron microscopy (SEM) investigations showed a nucleation process of calcium containing crystals and formation of bone-like apatite layer on the surface of HAp/Ag ceramic scaffolds. SEM microphotographs showed that the formed apatite layer on the dense HAp/Ag scaffolds was thicker if compared with porous HAp/Ag ceramic scaffolds. Significant differences in the formation process of bone-like apatite layer could be attributed to the differences of scaffold porosity, surface morphology and distribution of silver particles throughout the HAp/Ag ceramic scaffolds.
Keywords: hydroxyapatite, silver, in vitro, bioactivity, sbf solution