Abstract: Poly(vinylidene fluoride) (PVDF) hollow fiber with asymmetric sponge-like structure was fabricated through immersion precipitation. The extrusion speed ratio and the type of dope solvent used in the spinning of hollow fiber were investigated. The extrusion speed ratios of 2:1, 4:1, and 8:1 were chosen for investigation, while two different solvents which were N-methyl-2-pyrrolidone (NMP) and N,N-dimethylacetamide (DMAc). These two solvents were used for polymer dope preparation. The highest extrusion speed ratio (8:1) showed the best feature required and hence it was chosen to investigate the effect of the different solvents. Investigations revealed higher extrusion speed ratio with the lowest extrusion speed successfully avoided die swell phenomenon, and produced asymmetric sponge-like membrane with high mechanical strength. With the application DMAc as solvent, macrovoids were significantly reduced and mechanical strength was increased. The results showed that the manipulation of the spinning conditions which were essential for hollow fiber fabrication to acquire distinctive characteristics for various industrial applications.