BIOTECHNOLOGICAL METHOD OF IMMUNE REAGENTS DEVELOPMENT ON THE BASIS OF ANTI-IDIOTYPIC ANTIBODIES
Saule G. Ospanova
Pages: 153-160
Published: 1 Jan 2013
Views: 249
Downloads: 16
Abstract: The studying of anti-idiotypic antibodies and their Fab-fragments properties as the basis for the development of biologically safe, effective immunological preparations is the aim of research. Several strains of hybridomas cells producing a monoclonal anti-idiotypic antibodies to Brucella antigen were obtained. Investigations by ELISA and immuno-diffusion reactions showed that in a population of monoclonal anti-idiotypic antibodies there are At2ȕ antibodies that can be used as a "prototype" Brucella antigen. It is planned to study diagnostic properties of anti-idiotypic antibodies and their Fab - fragments with the purpose of making of Brucella antigen immunochemical analogs.
Keywords: anti-idiotypic antibodies, fab-fragments, immunological preparations, hybridomas cells, monoclonal anti-idiotypic antibodies, o brucella antigen
Cite this article: Saule G. Ospanova. BIOTECHNOLOGICAL METHOD OF IMMUNE REAGENTS DEVELOPMENT ON THE BASIS OF ANTI-IDIOTYPIC ANTIBODIES. Journal of International Scientific Publications: Agriculture & Food 1, 153-160 (2013). https://www.scientific-publications.net/en/article/1002947/
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