International Scientific Publications
© 2020 Science Events Ltd
Terms of Use  ·  Privacy Policy
Choose language English French Russian Bulgarian
Conference room
Materials, Methods & Technologies 2020, 22nd International Conference
29 August - 1 September, Burgas, Bulgaria
Call for Papers

Materials, Methods & Technologies, Volume 13, 2019

SYNTHESIS AND IN SILICO STUDY OF NEW KETOPROFEN DERIVATIVES
Stanimir P. Manolov, Iliyan I. Ivanov, Valery A. Mollov, Dimitar G. Bojilov
Pages: 250-261
Published: 18 Sep 2019
Views: 817
Downloads: 52
Abstract: Ketoprofen is a widespread non-steroidal anti-inflammatory agent used in treatment of acute pain and chronic arthritis. On the other hand, isoquinoline alkaloids are very well known with their wide range of biological activities. From this point of view it is of interest to us to obtain new isoquinolines containing a ketoprofen residue in their structure as new substances with potential biological activity. To estimate general efficacy and safety of the newly obtained compounds, their biological potential has been evaluated.
Keywords: ketoprofen, nsaids, 1,2,3,4-tetrahydroisoquinoline, in silico, α-amidoalkylation reaction, tfoh/sio2, heterogeneous catalysis
Download full text

Back to the contents of the volume
By using this site you agree to our Privacy Policy and Terms of Use. We use cookies, including for analytics, personalisation, and ads.